Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

S Srivastav, S Neupane, S Bhurtel, N Katila… - The Journal of …, 2019 - Elsevier
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic
effects on functions of the central nervous system via microbiota-gut-brain axis. However, no
studies displayed the neuroprotective effects of probiotics in the Parkinson's disease. This
study aimed to test the neuroprotective effects of probiotics in two different models of PD. We
evaluated neuroprotective effects of a probiotic cocktail containing Lactobacillus rhamnosus …

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity.

SS Sunil Srivastav, S Neupane, SB Sunil Bhurtel… - 2019 - cabidigitallibrary.org
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic
effects on functions of the central nervous system via microbiota-gut-brain axis. However, no
studies displayed the neuroprotective effects of probiotics in the Parkinson's disease. This
study aimed to test the neuroprotective effects of probiotics in two different models of PD. We
evaluated neuroprotective effects of a probiotic cocktail containing Lactobacillus rhamnosus …
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