… Candidalysin is derived from its parent protein Ece1p. Here, we identify two key amino …
Ece1p vital for processing and production of candidalysin. Mutations of these residues render C. …

… Candidalysin is derived from its parent protein Ece1p. Here, we identify two key amino …
Ece1p vital for processing and production of candidalysin. Mutations of these residues render C. …

… This region of Ece1p was considered the first fungal peptide … hyphae is an essential virulence
attribute of C albicans; the … candidalysin has on other pathogenicity factors in C albicans, …

… ) encoded by the ECE1 gene, plays a crucial role in driving … if expression and/or processing
of Ece1p differs across C. … expression and/or processing of candidalysin differs across C. …

… The opportunistic fungal pathogen Candida albicans … ) which are critical determinants of
staphylococcal virulence, tend … proper processing of the signal peptide 32 and thus essential for …

… Key Contribution: This manuscript focuses on the fungal peptide toxin candidalysin. It …
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence…

… Candidalysin is secreted by Candida albicans and is critical … proteolytic processing of the
hypha-associated protein Ece1p … candidalysin potency and fungal pathogenicity of these three …

… Candida albicans is one of the most dangerous fungi to … 18-24 hours at 37C before being
processed for DNA extraction and … albicans Ece1p Is Critical for Candidalysin Maturation and …

… form of the human pathogenic fungus, Candida albicans. … Candidalysin is regarded as the
first true classical virulence … other KR processing sites within Ece1p, was critical for peptide …

… pathogen Candida albicans contributes heavily to its virulence. The peptide is derived …
Processing of Candida albicans Ece1p is critical for candidalysin maturation and fungal virulence…