Prognostic value of β1 integrin expression in metastatic melanoma
P Vihinen, J Nikkola, T Vlaykova… - Melanoma …, 2000 - journals.lww.com
The expression of integrin-type cell adhesion receptors is frequently changed in malignant
transformation. Despite their important role in cancer cell behaviour, the value of integrins as
prognostic markers is mostly unknown. We have examined the expression of [beta] 1
integrins in 38 metastatic melanomas obtained from 27 patients treated with combined
chemoimmunotherapy. On the basis of [beta] 1 integrin expression, the melanoma samples
were divided into two groups:[beta] 1-negative tumours (< 10%[beta] 1 integrin …
transformation. Despite their important role in cancer cell behaviour, the value of integrins as
prognostic markers is mostly unknown. We have examined the expression of [beta] 1
integrins in 38 metastatic melanomas obtained from 27 patients treated with combined
chemoimmunotherapy. On the basis of [beta] 1 integrin expression, the melanoma samples
were divided into two groups:[beta] 1-negative tumours (< 10%[beta] 1 integrin …
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