The aim of this study was to investigate the protective effect of melatonin (2.5 mg/kg/day,
given to rats five times by intra-peritoneal injection) against damage in bone-marrow
chromosomes induced by a single dose of gamma radiation (4.0 Gy whole-body irradiation;
WBI). Ninety-six male albino rats were divided into four equal groups of 24 rats each. They
were designated as I—non-irradiated, non-treated control rats, II—non-irradiated rats treated
with melatonin for five successive days, III—whole-body gamma-irradiated rats and IV—rats …