Protective effects of metformin against aluminum phosphide-induced acute hepato-renal damage in rats: an experimental approach
MR Khezri, R Varzandeh… - Pesticide Biochemistry …, 2022 - Elsevier
Abstract Phosphine (PH3), from hydrolysis of magnesium, zinc, and aluminum phosphide
(AlP), is a rodenticide and insecticide which is used to avoid losses of the agriculture
products. However, using of this agent may affect the human health, in a way that poisoning
with AlP has a high rate of mortality and morbidities. This study determined the ameliorative
effects of metformin (MET) on AlP-induced hepato-and nephro-toxicity in Wistar rats. Male
rats were randomly divided into four experimental groups. Group I was the control group …
(AlP), is a rodenticide and insecticide which is used to avoid losses of the agriculture
products. However, using of this agent may affect the human health, in a way that poisoning
with AlP has a high rate of mortality and morbidities. This study determined the ameliorative
effects of metformin (MET) on AlP-induced hepato-and nephro-toxicity in Wistar rats. Male
rats were randomly divided into four experimental groups. Group I was the control group …
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