Structure, mechanism and regulation of pyruvate carboxylase

S Jitrapakdee, M St Maurice, I Rayment… - Biochemical …, 2008 - portlandpress.com
pyruvate carboxylase) is a biotin-containing enzyme that catalyses the HCO 3 − - and
MgATP-dependent carboxylation of pyruvate … of the biotin carboxylase, carboxyltransferase and …

Pyruvate carboxylase

JC Wallace, S Jitrapakdee… - The international journal of …, 1998 - Elsevier
carboxylases and is found widely among eukaryotic tissues and in many prokaryotic species.
It catalyses the ATP-dependent carboxylation of pyruvate to … of pyruvate carboxylase in the …

Structure, function and regulation of pyruvate carboxylase

S Jitrapakdee, JC Wallace - Biochemical Journal, 1999 - portlandpress.com
… the ATP-dependent carboxylation of pyruvate to oxaloacetate. … functional domains: the biotin
carboxylation domain, the … activity or in the rate of pyruvate carboxylation in the short term. …

The structure and the mechanism of action of pyruvate carboxylase

PV Attwood - The international journal of biochemistry & cell biology, 1995 - Elsevier
Pyruvate carboxylase plays an important role in intewnedhuy metabolism, ctrtaiysing the
formation of oxaloncetate from pyruvate … The overall reaction catalysed by pyruvate carboxylase

Pyruvate carboxylase

MF UTTER, MC SCRUTTON - Current topics in cellular regulation, 1969 - Elsevier
… of action, the structure, and the regulation of the catalytic activity of pyruvate carboxylase.
Pyruvate carboxylases have been purified from chicken liver mitochon dria (69, 87), turkey and …

Pyruvate carboxylase

PV ATTWOOD, DB KEECH - Current topics in cellular regulation, 1984 - Elsevier
… that the active site of pyruvate carboxylase isolated from this source … The situation with regard
to pyruvate carboxylases isolated … Pyruvate carboxylases isolated from the liver of several …

1 Pyruvate Carboxylase

MC Scrutton, MR Young - The enzymes, 1972 - Elsevier
… exchange of "C-pyruvate with oxalacetate catalyzed by pyruvate carboxylase from rat liver (…
the rate of pyruvate-oxalacetate exchange by the other pyruvate carboxylases examined (27, …

Pyruvate carboxylase, structure and function

M Valle - Macromolecular Protein Complexes: Structure and …, 2017 - Springer
carboxylation of pyruvate into oxaloacetate, and a binding site for acetyl-CoA, an allosteric
regulator of the enzyme. Pyruvate carboxylase … findings on pyruvate carboxylase functioning …

Pyruvate carboxylase deficiency: mechanisms, mimics and anaplerosis

I Marin-Valencia, CR Roe, JM Pascual - Molecular genetics and …, 2010 - Elsevier
Pyruvate carboxylase (PC) is a regulated mitochondrial enzyme that catalyzes the
conversion of pyruvate to oxaloacetate, a critical transition that replenishes citric acid cycle …

[HTML][HTML] Inhibitors of pyruvate carboxylase

TN Zeczycki, MS Maurice… - The open enzyme …, 2010 - ncbi.nlm.nih.gov
… inhibitor with respect to pyruvate in the overall pyruvate carboxylation reaction (K i = 1.6 mM)…
inhibition with respect to pyruvate was observed for the pyruvate carboxylation reaction, but …