8 天前 - … RIG-I senses double-stranded RNA (dsRNA) and induces the … immune response
against RNA viruses [43]. Subsequently, RIG-I was found to detect the dsRNA of multiple RNA …

24 天前 - … RIG-I uses to facilitate viral RNA sensing and regulate downstream activation of
the immune … (2014) Antiviral immunity via RIG-I-mediated recognition of RNA bearing 50-…

42 天前 - … of the immune system. This is particularly important for the RIG-I-like receptors (RLRs),
which recognize viral dsRNA and initiate antiviral innate immune responses with the …

63 天前 - … of a RIG-I homolog. Additionally, STING, a member of the dsDNA sensing pathway
was … Despite the advances in our knowledge of anti-viral immune counterpart genes in …

92 天前 - … such as RIGI (RNA sensor RIG-I)-like … the antiviral immune response and autophagy
( Figure 7E ): Upon infection by PEDV or rPEDV-Δnsp2, host MDA5/RIGI senses viral RNA …

105 天前 - … In contrast, HCV sensing by Retinoic acid-Inducible Gene I (RIG-I) and MDA5 was
entirely blocked by the efficient cleavage of the RLRs adaptor protein MAVS, leading to the …

119 天前 - … are recognized by cellular sensor proteins known as … extensively studied for their
antiviral activities during viral … within the host, according to the RIG-I-like receptor-induced IRF3 …

122 天前 - … , and mitochondrial antiviral signaling (MAVS)-… RNA sensor and activated IFN-I
transcription through STING. So, in this study, we investigated whether IFI16 regulated RNA-RIG-I…

181 天前 - … the question of how the cytoplasmic RNA sensor RIG-I detects a nuclear-… RIG-I
(nRIG-I) -mediated IAV sensing initiates an antiviral IFN signaling in a mitochondrial antiviral …

205 天前 - … the dsRNA sensor RIG-I in the cytoplasm. … antiviral immunity to protect neuronal
cells from viral infection. This example emphasizes the need to carefully evaluate different …