过去一年中添加的文章，按日期排序
Plant-Derived Compounds with Therapeutic Potential for the Treatment of Human Coronavirus Diseases
IO Adewale, OG Famutimi, O Osiebe - Proceedings of the National …, 2024 - Springer
9 天前 - … the second-best drug that can alter the genetic makeup in SARS-CoV-2-infected
cells [7]. … , the use of glycyrrhizin to target ACE2 may well be a good strategy in COVID-19 …
cells [7]. … , the use of glycyrrhizin to target ACE2 may well be a good strategy in COVID-19 …
Green synthesis of medicine and development of inhibitors for druggable proteins of SARS-COV-2
Q Chen - 2024 - theses.lib.polyu.edu.hk
13 天前 - … of SARS-CoV-2 variants would be achievable. Here, our discussion mainly focuses
on two target proteins: nsp12 (RNA dependent RNA … as an anti-SARS-CoV-2 drug target. …
on two target proteins: nsp12 (RNA dependent RNA … as an anti-SARS-CoV-2 drug target. …
… MECHANISMS OF PATHOGENIC PROTEINS AND DESIGNING NOVEL INHIBITORS AGAINST MYCOBACTERIUM TUBERCULOSIS AND SARS-COV-2
JD Carbone - 2024 - rdw.rowan.edu
16 天前 - … In Chapter 2, CADD methods lead to development of inhibitors targeting the RNA
Dependent RNA Polymerase (RdRP) of SARS-CoV-2. Inspired by the nucleotide inhibitor …
Dependent RNA Polymerase (RdRP) of SARS-CoV-2. Inspired by the nucleotide inhibitor …
Using computer-aided drug design (CADD) methods for investigating the mechanism of polyphenols and identifying drug candidates against COVID-19
Y Wu - esploro.libs.uga.edu
24 天前 - … these targets. To further develop potential drugs against COVID-19, we also virtually
screened 728 approved drugs and 26,193 compounds for COVID-19 drug discovery. The …
screened 728 approved drugs and 26,193 compounds for COVID-19 drug discovery. The …
Viral Vectors for Gene Therapy, Cancer, and SARS-CoV-2
G Dagotto - 2024 - dash.harvard.edu
29 天前 - … the goal of generating a broadly protective sarbecovirus vaccine. A portion of
the sarbecovirus RNA-dependent RNA polymerase … challenge by mouse adapted SARS-CoV-2. …
the sarbecovirus RNA-dependent RNA polymerase … challenge by mouse adapted SARS-CoV-2. …
Anti-SARS-CoV-2 Activity of Flavonols and Their Glycosylated Derivatives
34 天前 - … like ACE2, TMPRSS2, and furin have been identified as potential drug targets for
COVID‑19. • Promising intracellular targets for potential drugs include 3CLpro (or Mpro), PLpro…
COVID‑19. • Promising intracellular targets for potential drugs include 3CLpro (or Mpro), PLpro…
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses
DR Martinez, FR Moreira, NJ Catanzaro… - Science Translational …, 2024 - science.org
38 天前 - … SARS-CoV-2 target one of two viral proteins. Remdesivir and molnupiravir target the
RNA-dependent RNA polymerase … antiviral agent of Paxlovid) targets the main protease (M …
RNA-dependent RNA polymerase … antiviral agent of Paxlovid) targets the main protease (M …
Broad-spectrum RNA prophylactic and therapeutic interventions for SARS-CoV-2
A Gontu - 2024 - etda.libraries.psu.edu
45 天前 - … urgent need to develop SARS-CoV-2 vaccines and therapeutics that are … goal of
this thesis was to develop a broad-spectrum RNA-based SARS-CoV-2 vaccine and therapeutic. …
this thesis was to develop a broad-spectrum RNA-based SARS-CoV-2 vaccine and therapeutic. …
In silico screening and identification of lead molecules from Garcinia gummi-gutta with multitarget activity against SARS-CoV-2
KJ Sugathan, S Sreekumar… - Journal of Applied …, 2024 - japsonline.com
51 天前 - … were tested against three therapeutic targets of SARS-CoV-2, namely … RNA-dependent
RNA polymerase, and two human host targets such as angiotensin-converting enzyme-2 …
RNA polymerase, and two human host targets such as angiotensin-converting enzyme-2 …
Exploring molecular recognition of small molecule binding, protein-protein interactions, and RNA folding dynamics using enhanced sampling methods
A VIJAY - 2024 - dr.iiserpune.ac.in
51 天前 - … targeting SARS-CoV-2 virus-based systems (spike protein and RNA-dependent RNA
polymerase… the potential strong binders to the target mentioned above. A similar approach …
polymerase… the potential strong binders to the target mentioned above. A similar approach …