… measure free radical production in the beating heart. However, we believe that our results
do justify further consideration of the role of free radicals in myocardial injury and protection. …

… free radicals are generated in the reperfused heart via Fenton chemistry. These radicals …
Time course experiment of free radical generation in a heart reperfused after 30 min of 37 "C …

… to directly measure and characterize free radical generation in the heart. Studies from our …
of radical generation on reperfusion of the ischemic heart. In our early studies only one radical …

… this, there is a burst of free radical production in the myocardium. This sudden increase in
free radical content is not observed when the hearts are reperfused initially with anoxic buffer. …

… free-radical activity, and antioxidants have received much attention as a potential therapy
for conditions ranging from aging to cancer and coronary heart disease. A free radical is any …

… We believe that free radicals are involved in the genesis of heart failure. In congestive heart
… generate free radicals."4 Support for this hypothesis comes from work in animal models of …

… significance of free radicals, oxidative stress, … radicals as well as oxidative stress have
been cited, better methods to study the quantity as well as subcellular distribution of free radicals …

… -induced arrhythmias in control hearts and hearts treated with PBN. Hearts (12 for each group…
The results were compared to PBNfree control hearts. In each instance, a bell-shaped time-…

… free radicals in liver and heart in vivo. The radicals are believed to be carbon-centered radicals,
… The radicals in the liver were demonstrated to be localized in the endoplasmic reticulum. …

… H 2 O 2 , and hydroxy radical (·OH) in failing myocardial tissue. Heart failure was
produced in … myocardial tissue homogenates were reacted with the nitroxide radical, 4-hydroxy-2,2,6,6,-…