BACKGROUND AND PURPOSE: The purpose was to develop a systematic review that
would address the following question: what is the role of radiopharmaceuticals in the
palliation of metastatic bone pain in adults with uncomplicated, multifocal painful bone
metastases whose pain is not controlled with conventional analgesic regimens? The
outcomes of interest are pain response, analgesic consumption, overall survival, adverse
effects and quality of life. MATERIALS AND METHODS: A systematic review of the English …