Randomisation to protect against selection bias in healthcare trials
R Kunz, GE Vist, AD Oxman - Cochrane database of …, 2007 - cochranelibrary.com
Background Randomised trials use the play of chance to assign participants to comparison
groups. The unpredictability of the process, if not subverted, should prevent systematic
differences between comparison groups (selection bias), provided that a sufficient number of
people are randomised. Objectives To assess the effects of randomisation and concealment
of allocation on the results of healthcare trials.
groups. The unpredictability of the process, if not subverted, should prevent systematic
differences between comparison groups (selection bias), provided that a sufficient number of
people are randomised. Objectives To assess the effects of randomisation and concealment
of allocation on the results of healthcare trials.
Randomisation to protect against selection bias in healthcare trials
J Odgaard‐Jensen, GE Vist, A Timmer… - Cochrane database …, 2011 - cochranelibrary.com
Background Randomised trials use the play of chance to assign participants to comparison
groups. The unpredictability of the process, if not subverted, should prevent systematic
differences between comparison groups (selection bias). Differences due to chance will still
occur and these are minimised by randomising a sufficiently large number of people.
Objectives To assess the effects of randomisation and concealment of allocation on the
results of healthcare studies.
groups. The unpredictability of the process, if not subverted, should prevent systematic
differences between comparison groups (selection bias). Differences due to chance will still
occur and these are minimised by randomising a sufficiently large number of people.
Objectives To assess the effects of randomisation and concealment of allocation on the
results of healthcare studies.
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