Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug …

TJ Smith, PS Staats, T Deer, LJ Stearns… - Journal of Clinical …, 2002 - ascopubs.org
PURPOSE: Implantable intrathecal drug delivery systems (IDDSs) have been used to … no
randomized clinical trial (RCT) data comparing them with comprehensive medical management …

[HTML][HTML] An implantable drug delivery system (IDDS) for refractory cancer pain provides sustained pain control, less drug-related toxicity, and possibly better survival …

…, Implantable Drug Delivery Systems Study Group - Annals of …, 2005 - Elsevier
randomized clinical trial of implantable drug delivery systems (IDDS) plus comprehensive
medical … with a programmable, implantable drug delivery system (IDDS) supplemented with …

What is the evidence for implantable drug delivery systems for refractory cancer pain?

TJ Smith, P Coyne - Supportive Cancer Therapy, 2004 - Elsevier
… We performed a large, randomized clinical trial with high statistical power to evaluate the
effectiveness of comprehensive medical management (CMM) compared with CMM plus IDDS …

Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema

JA Haller, BD Kuppermann… - Archives of …, 2010 - jamanetwork.com
… Dexamethasone DDS was surgically implanted into the vitreous … After placement of the
implant, the scleral and conjunctival … Haller had full access to all of the data in the study and takes …

[HTML][HTML] Intrathecal drug delivery systems for cancer pain: an analysis of a prospective, multicenter product surveillance registry

LM Stearns, A Abd-Elsayed, C Perruchoud… - Anesthesia & …, 2020 - journals.lww.com
… pain have been demonstrated in randomized controlled clinical trials (RCTs). … Randomized
clinical trial of an implantable drug delivery system compared with comprehensive medical

Wearable and implantable devices for drug delivery: Applications and challenges

A Kar, N Ahamad, M Dewani, L Awasthi, R Patil… - Biomaterials, 2022 - Elsevier
… even in the controlled environment like clinical trials adhere to … the emerging concept of
such drug delivery devices with respect to their … Overall, this review provides a comprehensive

Intrathecal drug delivery systems for refractory pancreatic cancer pain: observational follow-up study over an 11-year period in a comprehensive cancer center

G Carvajal, D Dupoiron, V Seegers… - Anesthesia & …, 2018 - journals.lww.com
… Smith TJ, Staats PS, Deer T, et al.; Implantable Drug Delivery Systems StudyRandomized
clinical trial of an implantable drug delivery system compared with comprehensive medical

[PDF][PDF] Comprehensive consensus based guidelines on intrathecal drug delivery systems in the treatment of pain caused by cancer pain

TR Deer, HS Smith, AW Burton, JE Pope… - Pain …, 2011 - researchgate.net
… have evaluated the use of implantable drug delivery systems in patients at the … Randomized
clinical trial of an implantable drug delivery system compared with comprehensive medical

… long-term outcome study, comparing intrathecal (IT) boluses with continuous infusion trialing techniques prior to implantation of drug delivery systems (DDS) for the …

M Hamza, DM Doleys, IA Saleh, A Medvedovsky… - … : Technology at the …, 2015 - Elsevier
trial, patients were discharged to complete the weaning protocol after they were completely
off all opioids for ten days IDDS was implanted. … existed rather than a placebo-controlled trial. …

Implantable drug delivery systems and foreign body reaction: Traversing the current clinical landscape

A Fayzullin, A Bakulina, K Mikaelyan, A Shekhter… - Bioengineering, 2021 - mdpi.com
… To the best of our knowledge, the information accumulated here is comprehensive and up …
-four-week results of a multicenter randomized clinical study. Ophthalmology 2006, 113, 1020–…