[HTML][HTML] Randomized controlled trial of clopidogrel to prevent primary arteriovenous fistula failure in hemodialysis patients

A Ghorbani, M Aalamshah, H Shahbazian… - Indian journal of …, 2009 - journals.lww.com
The optimal vascular access for chronic maintenance hemodialysis is the arteriovenous
fistula (AVF). Several studies suggest a role for antiplatelet agents in the prevention of
primary AVF failure. A double-blind, randomized trial was conducted to assess the efficacy
and safety of clopidogrel in hemodialysis patients. Ninety three patients were randomized to
receive 75 mg/daily of clopidogrel or placebo. The treatment was initiated 7–10 days prior to
scheduled access surgery and continued up to six weeks postoperatively, and then patients …
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