Rapid Responses and Mechanism of Action for Low-Dose Bisphenol S on ex Vivo Rat Hearts and Isolated Myocytes: Evidence of Female-Specific Proarrhythmic …
Background Bisphenol S (BPS) has increasingly been used as a substitute for bisphenol A
(BPA) in some “BPA-free” consumer goods and in thermal papers. Wide human exposure to
BPS has been reported; however, the biological and potential toxic effects of BPS are poorly
understood. Objective In this study, we sought to elucidate the sex-specific rapid effect of
BPS in rat hearts and its underlying mechanism. Methods We examined the rapid effects of
BPS in rat hearts using electrophysiology, confocal and conventional fluorescence imaging …
(BPA) in some “BPA-free” consumer goods and in thermal papers. Wide human exposure to
BPS has been reported; however, the biological and potential toxic effects of BPS are poorly
understood. Objective In this study, we sought to elucidate the sex-specific rapid effect of
BPS in rat hearts and its underlying mechanism. Methods We examined the rapid effects of
BPS in rat hearts using electrophysiology, confocal and conventional fluorescence imaging …
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