Rat models of bone metastases

S Blouin, MF Baslé, D Chappard - Clinical & experimental metastasis, 2005 - Springer
bone circulation, biocompatibility of prosthetic materials... In this review, we focused on rat as
a model for bone metastases: the size of the rat bone … the detection of bone metastases is X-…

Animal models of bone metastasis

TJ Rosol, SH Tannehill‐Gregg… - … Journal of the …, 2003 - Wiley Online Library
rat Dunning prostate carcinoma (R3327) has been used as a reliable model for bone metastasis
… injection of MatLyLu cells due to metastases in the lumbar vertebrae.32 The osteolytic …

New model for the induction of osteoblastic bone metastases in rat

K Liepe, H Geidel, M Haase, OW Hakenberg… - Anticancer …, 2005 - ar.iiarjournals.org
… improving treatment of hormone-refractory metastatic prostate cancer. In this study, we
investigated a new model for osteoblastic bone metastases. This model is necessary for further …

Animal models of bone metastasis

JK Simmons, BE Hildreth III, W Supsavhad… - Veterinary …, 2015 - journals.sagepub.com
metastatic pathway, and clinical applicability of the model. This review describes in vivo animal
models available for bone metastasisBone metastasis in rat models of prostate cancer is …

Use of bisphosphonates for the treatment of bone metastasis in experimental animal models

T Yoneda, T Michigami, B Yi… - Cancer …, 1999 - cancertreatmentreviews.com
… two animal models of bone metastasis (orthotopic and experimental). Using these models,
we … with anti-cancer agents on the metastasis of breast cancer to bone and visceral organs. In …

A rat model of bone cancer pain

SJ Medhurst, K Walker, M Bowes, BL Kidd, M Glatt… - Pain, 2002 - journals.lww.com
… In summary, the induction of bone cancer in the rat by the syngeneic MRMT-1 mammary
tumour cell line provides a valid pre-clinical model for pain associated with bone metastases. …

… of a rat model with site‐specific bone metastasis induced by MDA‐MB‐231 breast cancer cells and its application to the effects of an antibody against bone …

T Bäuerle, H Adwan, F Kiessling… - … journal of cancer, 2005 - Wiley Online Library
… a physiologically relevant animal model that is characterized by … this animal model to the
effects of an antibody against bone … In conclusion, the novel rat model for site-specific osteolytic …

Relations between radiograph texture analysis and microcomputed tomography in two rat models of bone metastases

S Blouin, MF Moreau, MF Baslé, D Chappard - Cells Tissues Organs, 2006 - karger.com
… osteoblastic bone metastases by microCT and to explore the X-ray images of the same bones
… Two malignant cell lines capable of inducing bone metastases were used in the present …

Nude rat model for studying metastasis of human tumor cells to bone and bone marrow

I Kjønniksen, JM Nesland, A Pihl… - JNCI: Journal of the …, 1990 - academic.oup.com
… significantly lower in bone than in lung, kidney, and liver, the pattern of metastases could not
… Researchers may find the model useful for studying the biology of bone metastases and for …

Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system

DG Hall, G Stoica - Journal of Bone and Mineral Research, 1994 - academic.oup.com
… The purpose of this work was to evaluate the effect of risedronate treatment on bone metastases
produced in a rat breast cancer model. Berlin Druckrey IV rats inoculated with ENU1564 …