Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
S Kato, KH Kim, HJ Lim, A Boichard… - Nature …, 2020 - nature.com
… Hence, our MTB reflects a real-world experience with molecular profiling and patient … the
outcome of 715 patients with advanced cancer presented at our MTB, and demonstrate that …
outcome of 715 patients with advanced cancer presented at our MTB, and demonstrate that …
Real-world data from a molecular tumor board: improved outcomes in breast and gynecologic cancers patients with precision medicine
LM Charo, RN Eskander, J Sicklick, KH Kim… - JCO Precision …, 2022 - ascopubs.org
… showed low positivity (5%, Ventana SP142). The case was discussed at the Molecular Tumor
Board … CT 2.5 months after therapy was initiated showed partial response (left to right, best …
Board … CT 2.5 months after therapy was initiated showed partial response (left to right, best …
The molecular tumor board: a tool for the governance of precision oncology in the real world
L Incorvaia, A Russo, S Cinieri - Tumori Journal, 2022 - journals.sagepub.com
… real-world experiences of MTBs suggest that patients treated with the MTB-recommended
regimen according to their tumor molecular alterations showed better outcome in … of precision …
regimen according to their tumor molecular alterations showed better outcome in … of precision …
A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients
… improves patient outcomes, as has been demonstrated in previous biomarker-driven studies.
Data … Here, we have presented the development, real-world implementation and testing of …
Data … Here, we have presented the development, real-world implementation and testing of …
Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards
DT Rieke, T de Bortoli, P Horak, M Lamping, M Benary… - BMC medicine, 2022 - Springer
… of molecular data presents a current challenge for precision … The left panel indicates genes
that were identified at least … The retrospective, real-world design of this study reduced the …
that were identified at least … The retrospective, real-world design of this study reduced the …
Molecular tumor board–assisted care in an advanced cancer population: results of a phase II clinical trial
RW Miller, ML Hutchcraft, HL Weiss, J Wu… - JCO Precision …, 2022 - ascopubs.org
… , most patients experienced improved PFS compared with … to improve outcomes for
patients with advanced cancer. … study demonstrates that patients with advanced cancer with …
patients with advanced cancer. … study demonstrates that patients with advanced cancer with …
Collaborative, multidisciplinary evaluation of cancer variants through virtual molecular tumor boards informs local clinical practices
… molecular tumor boards are highlighted and demonstrate a … To support the wider integration
of precision medicine in cancer, … data visualization methods to improve usability of molecular …
of precision medicine in cancer, … data visualization methods to improve usability of molecular …
The Molecular Tumor Board of the Regina Elena National Cancer Institute: from accrual to treatment in real-world
P Giacomini, F Valenti, M Allegretti, M Pallocca… - Journal of Translational …, 2023 - Springer
… , acting in the context of structured precision oncology trials. … Figure 5f shows that tumor/patient-specific
factors may be … to NGS reports, we strived to improve on this. From August 2022 (…
factors may be … to NGS reports, we strived to improve on this. From August 2022 (…
Framework for implementing and tracking a molecular tumor board at a National Cancer Institute–designated comprehensive cancer center
… resources that support timely and accurate interpretation of next-… Figure 2 shows the
breakdown of VICC MTB cases by … conditions that increase the likelihood of developing cancer, …
breakdown of VICC MTB cases by … conditions that increase the likelihood of developing cancer, …
[HTML][HTML] Support of a molecular tumour board by an evidence-based decision management system for precision oncology
M Lamping, M Benary, S Leyvraz… - … Journal of Cancer, 2020 - Elsevier
… Each row shows the single nucleotide variant per patient and … of outcomes from this
heterogeneous real-world cohort. … that outcome from PO programs will gradually improve with …
heterogeneous real-world cohort. … that outcome from PO programs will gradually improve with …