Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

S Kato, KH Kim, HJ Lim, A Boichard… - Nature …, 2020 - nature.com
… Hence, our MTB reflects a real-world experience with molecular profiling and patient … the
outcome of 715 patients with advanced cancer presented at our MTB, and demonstrate that …

Real-world data from a molecular tumor board: improved outcomes in breast and gynecologic cancers patients with precision medicine

LM Charo, RN Eskander, J Sicklick, KH Kim… - JCO Precision …, 2022 - ascopubs.org
showed low positivity (5%, Ventana SP142). The case was discussed at the Molecular Tumor
Board … CT 2.5 months after therapy was initiated showed partial response (left to right, best …

The molecular tumor board: a tool for the governance of precision oncology in the real world

L Incorvaia, A Russo, S Cinieri - Tumori Journal, 2022 - journals.sagepub.com
real-world experiences of MTBs suggest that patients treated with the MTB-recommended
regimen according to their tumor molecular alterations showed better outcome in … of precision

A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients

MJ Pishvaian, EM Blais, RJ Bender, S Rao… - JAMIA …, 2019 - academic.oup.com
improves patient outcomes, as has been demonstrated in previous biomarker-driven studies.
Data … Here, we have presented the development, real-world implementation and testing of …

Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards

DT Rieke, T de Bortoli, P Horak, M Lamping, M Benary… - BMC medicine, 2022 - Springer
… of molecular data presents a current challenge for precision … The left panel indicates genes
that were identified at least … The retrospective, real-world design of this study reduced the …

Molecular tumor board–assisted care in an advanced cancer population: results of a phase II clinical trial

RW Miller, ML Hutchcraft, HL Weiss, J Wu… - JCO Precision …, 2022 - ascopubs.org
… , most patients experienced improved PFS compared with … to improve outcomes for
patients with advanced cancer. … study demonstrates that patients with advanced cancer with …

Collaborative, multidisciplinary evaluation of cancer variants through virtual molecular tumor boards informs local clinical practices

S Rao, B Pitel, AH Wagner, SM Boca… - JCO clinical cancer …, 2020 - ascopubs.org
molecular tumor boards are highlighted and demonstrate a … To support the wider integration
of precision medicine in cancer, … data visualization methods to improve usability of molecular

The Molecular Tumor Board of the Regina Elena National Cancer Institute: from accrual to treatment in real-world

P Giacomini, F Valenti, M Allegretti, M Pallocca… - Journal of Translational …, 2023 - Springer
… , acting in the context of structured precision oncology trials. … Figure 5f shows that tumor/patient-specific
factors may be … to NGS reports, we strived to improve on this. From August 2022 (…

Framework for implementing and tracking a molecular tumor board at a National Cancer Institute–designated comprehensive cancer center

NM Jain, L Schmalz, C Cann, A Holland… - The …, 2021 - academic.oup.com
… resources that support timely and accurate interpretation of next-… Figure 2 shows the
breakdown of VICC MTB cases by … conditions that increase the likelihood of developing cancer, …

[HTML][HTML] Support of a molecular tumour board by an evidence-based decision management system for precision oncology

M Lamping, M Benary, S Leyvraz… - … Journal of Cancer, 2020 - Elsevier
… Each row shows the single nucleotide variant per patient and … of outcomes from this
heterogeneous real-world cohort. … that outcome from PO programs will gradually improve with …