Recent developments in visible-light-catalyzed multicomponent trifluoromethylation of unsaturated carbon–carbon bonds

EH Oh, HJ Kim, SB Han - Synthesis, 2018 - thieme-connect.com
EH Oh, HJ Kim, SB Han
Synthesis, 2018thieme-connect.com
Trifluoromethylation has emerged as an important tool for modulating the molecular
chemical and physical properties in material, polymer, and medicinal chemistry. In particular,
photocatalyzed trifluoromethylation in the presence of visible-light irradiation has potentially
different activity under mild conditions compared with traditional methods. This review
summarizes the recent advances in trifluoromethylation with multiple bond system such as
alkynes and alkenes. 1 Introduction 2 Trifluoromethylating Reagents 3 Multicomponent …
Trifluoromethylation has emerged as an important tool for modulating the molecular chemical and physical properties in material, polymer, and medicinal chemistry. In particular, photocatalyzed trifluoromethylation in the presence of visible-light irradiation has potentially different activity under mild conditions compared with traditional methods. This review summarizes the recent advances in trifluoromethylation with multiple bond system such as alkynes and alkenes.
1 Introduction
2 Trifluoromethylating Reagents
3 Multicomponent Reactions of Alkynes
4 Multicomponent Reactions of Alkenes
5 Conclusion
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