… checkpoints for attenuating inflammasome signaling at multiple steps. Here we discuss the
various regulatory mechanisms that have evolved to keep inflammasome signaling in check …

… , which together, tightly control and modulate inflammasome activation. Here, we provide …
inflammasome biology, with a particular emphasis on the regulation of inflammasome signaling …

… to activate inflammasome by direct interaction with a bacterial surface protein (82), suggesting
that the Syk signaling plays a critical role in the regulation of inflammasome activation. …

… of these regulation mechanisms is a basis for therapeutic targeting to the inflammasome. We
… the mechanisms of NLRP3 inflammasome activation and its regulatory signaling pathways. …

… canonical and noncanonical inflammasome activation and … signaling mechanisms that
provide stringent regulation over the activation and effector functions of the inflammasome…

… mechanisms underlying the regulation of inflammasome signaling. In the present …
inflammasome assembly and activation upon sensing of diverse stimuli, as well as the tight …

… Many regulatory mechanisms have been identified to attenuate … signaling at multiple steps.
Here, we review the developments in the negative regulation of NLRP3 inflammasome that …

… and this can be achieved by regulating inflammasome activity. However, we have, as yet,
little understanding of the mechanisms of this regulation. In particular the negative feedbacks, …

… The innate immune inflammasome signaling cascade mediates the production of essential
proinflammatory cytokines interleukin-1β (IL-1β) and IL-18. These cytokines regulate hepatic …

… pyroptosis, inflammasomes can also … inflammasome signaling, cell death decisions, and
cytokine activation and secretion. Here, we provide an updated view of inflammasome signaling…