… overall proton relaxivity of Gd(III) based MRI contrast agents. For … The development of high
relaxivity contrast agents mainly … macromolecular agents, therefore, the inner sphere relaxivity …

… , to increase the relaxivity, r 1p , of a Gd contrast agent, one has … affects relaxivity. Indeed, it
has been demonstrated that the … commercial contrast agents, which have higher relaxivities at …

… Relaxivity and Solomon–Bloembergen–Morgan Theory Contrast agents are evaluated on the
basis of their relaxivity… increased in the presence of the agent at a given concentration. The …

… magnetic resonance imaging (MRI) contrast agents for next generation. The in vitro water
proton relaxivity… -folds) than that of the commercial MRI contrast agent, Magnevist (gadolinium−…

… methods, and the procedures devised to optimize the relaxivity. These involve the use of
Gd III … The increase in relaxivity of the individual Gd chelates leads to significant relaxivity …

… of contrast agent of metal concentration [M]. High relaxivity means that the contrast agent can
… Mn(II)-based complexes may be useful as the basis for high relaxivity MRI contrast agents. …

… the relaxivity parameters of the 4−HSA adduct by NMRD or 17 O NMR. Nevertheless, the
relaxivity … for the development of MRI contrast agents of increased relaxivity. Furthermore, the …

… enhancement due to an MRI contrast agent is described by the term relaxivity, defined as …
millimolar concentration of contrast agent applied. Gd-based contrast agents increase both the …

… Several methods for improving the MR relaxivity of magnetic nanoparticles (T 2 contrast
agents) have also been highlighted in this review paper. Iron oxide and doped-ferrites (MFe 2 O …

… [10] have found the highestr1 relaxivity for liposomes containing no cholesterol and low
content of Gd-chelate. In contrast, we observe a higher r1 relaxivity for the vesicles with …