Replacement of dietary saturated FAs by PUFAs in diet and reverse cholesterol transport
IK Lesna, P Suchanek, J Kovar, P Stavek… - Journal of lipid …, 2008 - ASBMB
Dietary intervention is the first and usually successful approach in the treatment of high LDL
cholesterol (LDL-C) concentration, but it is frequently accompanied by a decrease in HDL
concentration. We studied 14 male volunteers on two different diets, high saturated fatty acid
(SFA) and high PUFA, in a crossover design to test whether a decrease in HDL can affect
reverse cholesterol transport from relabeled macrophages. A significant decrease of LDL-C
(in mmol/l) after a PUFA diet compared with an SFA diet from 3.15±0.65 to 2.80±0.56 (P< …
cholesterol (LDL-C) concentration, but it is frequently accompanied by a decrease in HDL
concentration. We studied 14 male volunteers on two different diets, high saturated fatty acid
(SFA) and high PUFA, in a crossover design to test whether a decrease in HDL can affect
reverse cholesterol transport from relabeled macrophages. A significant decrease of LDL-C
(in mmol/l) after a PUFA diet compared with an SFA diet from 3.15±0.65 to 2.80±0.56 (P< …
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