Research ethics and the challenge of whole-genome sequencing
AL McGuire, T Caulfield, MK Cho - Nature Reviews Genetics, 2008 - nature.com
… ethical considerations. We propose specific recommendations for each of these ethically
controversial issues, which can be used to guide research practice and stimulate policy …
controversial issues, which can be used to guide research practice and stimulate policy …
[HTML][HTML] Research ethics recommendations for whole-genome research: consensus statement
T Caulfield, AL McGuire, M Cho, JA Buchanan… - … biology, 2008 - journals.plos.org
… We therefore convened an interdisciplinary consensus workshop to develop ethically
rigorous and practical guidance for investigators and research ethics boards. What follows …
rigorous and practical guidance for investigators and research ethics boards. What follows …
[HTML][HTML] Ethical implications of the use of whole genome methods in medical research
… such as whole genome sequencing methods is that it takes some time before a critical amount
of expertise is built up within the research ethics community to make approval for research …
of expertise is built up within the research ethics community to make approval for research …
[HTML][HTML] Informed consent for whole-genome sequencing studies in the clinical setting. Proposed recommendations on essential content and process
… statements. The following search strategy was used: (… OR whole-genome sequencing
OR whole genome sequencing … Consent OR consent) OR (Ethics OR ethical issues) OR (incidental …
OR whole genome sequencing … Consent OR consent) OR (Ethics OR ethical issues) OR (incidental …
Genomics really gets personal: how exome and whole genome sequencing challenge the ethical framework of human genetics research
HK Tabor, BE Berkman, SC Hull… - American Journal of …, 2011 - Wiley Online Library
… as to highlight the opportunities for the research, ethics and policy communities to … ethical
practices of existing or published ES/WGS studies or to make specific policy recommendations …
practices of existing or published ES/WGS studies or to make specific policy recommendations …
Ethical issues raised by whole genome sequencing
W Pinxten, HC Howard - Best Practice & Research Clinical …, 2014 - Elsevier
… Such an approach is consistent with the history of research ethics with human subjects. …
recommends that clinical sequencing laboratories have a duty, when performing whole genome …
recommends that clinical sequencing laboratories have a duty, when performing whole genome …
[HTML][HTML] Ethical and legal implications of whole genome and whole exome sequencing in African populations
… research subjects typically require ethical clearance from relevant institutional review boards
(IRBs) or research ethics … raised in this study as well as potential recommendations to help …
(IRBs) or research ethics … raised in this study as well as potential recommendations to help …
Findings made in gene panel to whole genome sequencing: data, knowledge, ethics–and consequences?
EC Winkler, S Wiemann - Expert review of molecular diagnostics, 2016 - Taylor & Francis
… Diverse kinds of sequencing approaches are applied, ranging from gene panel to whole-genome
sequencing. All these have proven successful in the identification of causal and …
sequencing. All these have proven successful in the identification of causal and …
[HTML][HTML] Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studies
MP Mackley, B Fletcher, M Parker, H Watkins… - Genetics in …, 2017 - Elsevier
… for the ACMG recommendations, opponents (and alternative guidelines from Europe and …
diseases in Canada: Position Statement of the Canadian College of Medical Geneticists …
diseases in Canada: Position Statement of the Canadian College of Medical Geneticists …
Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working …
RR Fabsitz, A McGuire, RR Sharp… - Circulation …, 2010 - Am Heart Assoc
… of a conference report and recommendations on returning genetic research results to … 4
High-throughput technologies have been developed, whole genome sequencing is a reality, …
High-throughput technologies have been developed, whole genome sequencing is a reality, …