Respiratory failure due to insufflated talc

JRM Campos, EC Werebe, FS Vargas, FB Jatene… - The Lancet, 1997 - thelancet.com
JRM Campos, EC Werebe, FS Vargas, FB Jatene, RW Light
The Lancet, 1997thelancet.com
252 Vol 349• January 25, 1997 can be found throughout the body. Previous reports3 have
suggested that respiratory difficulties after intrapleural talc are related to a high dose (about
10 g) talc, but our experience shows that respiratory failure and death can occur after doses
as low as 2 g of talc. 1 Vargas FS, Milanez JR, Filomeno LT, Fernandez A, Jatene A, Light
RW. Intrapleural talc for the prevention of recurrence in benign or undiagnosed pleural
effusion. Chest 1994; 106: 1771–75. 2 Milanez RC, Vargas FS, Filomeno LB, et al …
252 Vol 349• January 25, 1997 can be found throughout the body. Previous reports3 have suggested that respiratory difficulties after intrapleural talc are related to a high dose (about 10 g) talc, but our experience shows that respiratory failure and death can occur after doses as low as 2 g of talc.
1 Vargas FS, Milanez JR, Filomeno LT, Fernandez A, Jatene A, Light RW. Intrapleural talc for the prevention of recurrence in benign or undiagnosed pleural effusion. Chest 1994; 106: 1771–75. 2 Milanez RC, Vargas FS, Filomeno LB, et al. Intrapleural talc for the treatment of malignant pleural effusions secondary to breast cancer. Cancer 1995; 75: 2688–92.
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