Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients

CE van Iperen, CAJM Gaillard… - Critical care …, 2001 - journals.lww.com
Objectives Critically ill patients often are anemic, which may impair oxygen delivery.
Transfusion of red cells and supplementation with vitamins or iron are the usual therapeutic
strategies, whereas only sporadic data are available on the use of epoetin alfa in these
patients. We investigated endogenous erythropoietin (EPO) production and the response to
epoetin alfa in anemic intensive care unit (ICU) patients. Design
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