过去一年中添加的文章,按日期排序

LGG-07. MULTI-OMICS ANALYSIS IDENTIFIES MOLECULAR DRIVERS AND THERAPEUTIC TARGETS IN DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR …

M Mikkelsen, X Li, K Yu, A High, H Tran… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - … We sought to better describe the clinical characteristics of patients with DLGNT and
… 6), there were no responses and 2 progressions on therapy, compared to 1 response and 1 …

EPEN-16. BULK AND SINGLE-CELL SPATIAL CHARACTERIZATION OF THE TUMOR IMMUNE MICROENVIRONMENT OF POSTERIOR FOSSA GROUP A …

JAS Lammers, MEG Kranendonk, FG Calkoen… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - … and the spatial interplay between tumor and immune cells have not been elucidated.
Here, we aim to comprehensively characterize the … and the potential impact on response to

IMG-02. USING MRI RADIOMICS AND MACHINE LEARNING TO PREDICT OVERALL SURVIVAL FOR PEDIATRIC DIFFUSE MIDLINE GLIOMAS

X Liu, Z Jiang, HR Roth, SM Anwar, ER Bonner… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - the common noninvasive tool for DMG diagnosis and monitoring of tumor response
to … feature selection to select discriminative features based on the segmented volumes. Two …

… CAR T CELLS OVERCOMES DYSFUNCTIONAL IMMUNE SYNAPSE FORMATION AGAINST DIPGS, ENHANCING IN VITRO AND IN VIVO ANTITUMOR RESPONSE

J Ibanez, M Meehl, MB Ward, J Ocasio, S Baker… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - … , several limitations need to be addressed. The goal of this study is to identify why
CAR T … improving the immune synapse (IS), or the interaction between tumor and CAR T cells. …

LGG-25. ADVANCING RESPONSE ASSESSMENT OF LOW-GRADE GLIOMAS: IDENTIFYING VOLUME CORRELATIONS OF BI-PERPENDICULAR DIAMETER …

G Dumbrille, S Zhang, GW Robinson… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - … For the ANN, the predicted changes are +20%, -29%, -53%, and -78%. The
ANN demonstrated a lower MSE compared to the GLM. The two models showed higher …

LGG-05. REPORT ON PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC)-029B, A PROSPECTIVE PHASE 2 CLINICAL TRIAL OF SELUMETINIB IN TREATING …

J Fangusaro, A Onar-Thomas, TY Poussaint… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - to scientific literature. Inclusion in an NLM database does not imply endorsement
of, or agreement with, the contents by NLM or the … stability and responses among diverse …

… -92. IMMUNE ACTIVATION STUDIES WITH THE NEOANTIGEN-BASED PEPTIDE VACCINE RHSC-DIPGVAX DEMONSTRATE ANTIBODY-MEDIATED RESPONSES …

P Sipila, L Boland, JM Miska, SN Chi, M Sato… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - the phenomenon of epitope spreading, an extension of the immune response to
secondary epitopes not directly targeted by the therapy, thus promoting distinct, individualized …

IMMU-02. MODIFYING CAR T CELL EPIGENETIC PROGRAMS TO IMPROVE THEIR PERSISTENCE AGAINST GROUP 3 MEDULLOBLASTOMAS

MB Ward, L Senaoui, BA Youngblood… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - The goal of this study was to compare head-to-head … group 3 MB (G3MB), the most
malignant MB subtype. … mid , and D425 high but is insufficient to elicit curative responses. …

GCT-14. TREATMENT APPROACH FOR METASTATIC INTRACRANIAL GERMINOMA: A MULTI-INSTITUTIONAL EXPERIENCE

PC Power, KX Liu, SN Chi, KD Wright, KJ Marcus… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - the most common CNS germ cell tumor in children. Treatment with 24Gy craniospinal
irradiation (CSI) with boost to … had complete response, four patients had partial response, …

IMMU-06. CAR DESIGN SHAPES THE BRAIN TUMOR IMMUNE MICROENVIRONMENT: IMPACT ON ACTIVITY AND PERSISTENCE OF ANTI-GLIOMA ADOPTIVE T …

D Haydar, J Ibañez-Vega, J Crawford, Z Yi… - Neuro …, 2024 - ncbi.nlm.nih.gov
4 天前 - … have proven safe in clinical trials, yet no objective responses were observed in
patients. … , we set to optimize B7-H3 CAR structure and examine the effects of CAR design on the