Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome
… for contextual learning defects in Down syndrome, we examined the Ts65Dn mouse model.
… Given similar deficits in contextual learning in DS and the mouse model, we asked whether …
… Given similar deficits in contextual learning in DS and the mouse model, we asked whether …
[PDF][PDF] Restoration of Norepinephrine-Modulated Contextual Memory in
A Salehi - thedesignspace.net
… for contextual learning defects in Down syndrome, we examined the Ts65Dn mouse model.
… Given similar deficits in contextual learning in DS and the mouse model, we asked whether …
… Given similar deficits in contextual learning in DS and the mouse model, we asked whether …
Designer receptors enhance memory in a mouse model of Down syndrome
AM Fortress, ED Hamlett, EM Vazey… - Journal of …, 2015 - Soc Neuroscience
… ; however, spatial working memory was restored in Ts65Dn mice after l-DOPS treatment, …
agonist isoproterenol facilitates contextual fear memory in DβH-deficient mice, suggesting that …
agonist isoproterenol facilitates contextual fear memory in DβH-deficient mice, suggesting that …
Formoterol, a long-acting β2 adrenergic agonist, improves cognitive function and promotes dendritic complexity in a mouse model of Down syndrome
… of mouse models of AD could restore microglial functions and greater Aβ clearance in these
… , formoterol can significantly improve contextual learning in the Ts65Dn mouse model of DS. …
… , formoterol can significantly improve contextual learning in the Ts65Dn mouse model of DS. …
Hippocampal network alterations in Alzheimer's disease and Down syndrome: from structure to therapy
MM Sanchez, S Moghadam, P Naik… - Journal of …, 2011 - content.iospress.com
… restoring the proper function of this vulnerable neuronal population could be a successful
strategy in restoring the physiological role of the HC in mouse models … contextual memory …
strategy in restoring the physiological role of the HC in mouse models … contextual memory …
Noradrenergic system in down syndrome and Alzheimer's disease a target for therapy
… contextual learning in these mice. Also, we noted that treated … the recovery of motor function
and spatial memory after … receptors enhance memory in a mouse model of Down syndrome. …
and spatial memory after … receptors enhance memory in a mouse model of Down syndrome. …
Prospects for improving brain function in individuals with Down syndrome
ACS Costa, JJ Scott-McKean - CNS drugs, 2013 - Springer
… /memory deficits seen in mouse models of DS. Here, we will review the available mouse
models for … In another study, xamoterol effectively restored the memory deficit in contextual fear …
models for … In another study, xamoterol effectively restored the memory deficit in contextual fear …
Neurobiological elements of cognitive dysfunction in down syndrome: exploring the role of APP
MM Sanchez, SN Heyn, D Das, S Moghadam… - Biological …, 2012 - Elsevier
… in Down Syndrome and its mouse models. Unlike other … ) can restore contextual learning
in Ts65Dn mice. Ts65Dn … ) show a significant improvement in contextual memory. As a result, …
in Ts65Dn mice. Ts65Dn … ) show a significant improvement in contextual memory. As a result, …
Short-term treatment with flumazenil restores long-term object memory in a mouse model of Down syndrome
… can restore the ability of adult TS mice to succeed in the 24 h NOR test. Of note, the
Ts65Dn … picrotoxin restored LTP to normal levels in hippocampal slices from Ts65Dn mice. …
Ts65Dn … picrotoxin restored LTP to normal levels in hippocampal slices from Ts65Dn mice. …
A noradrenergic lesion exacerbates neurodegeneration in a Down syndrome mouse model
J Lockrow, H Boger, G Gerhardt… - Journal of …, 2011 - content.iospress.com
… negatively affect spatial memory function in intact rodents, it potentiates memory deficits in
… leading to enhanced neuropathology and memory loss in transgenic AD mouse models [9]. …
… leading to enhanced neuropathology and memory loss in transgenic AD mouse models [9]. …