Reversal by quercetin of corticotrophin releasing factor induced anxiety-and depression-like effect in mice

P Bhutada, Y Mundhada, K Bansod, A Ubgade… - Progress in Neuro …, 2010 - Elsevier
Quercetin is a bioflavonoid reported to produce variety of behavioral effects like anxiolytic,
antidepressant, etc. Recent gathering evidences indicated that quercetin attenuates stress-
induced behavioral and biochemical effects. It also decreases CRF expression in the brain.
As CRF is commonly implicated in the high-anxiety and depression, we hypothesized that
quercetin may involve CRF in its anxiolytic-and antidepressant-like effects. To support such
possibility, we investigated the influence of quercetin on CRF or CRF antagonist …

Reversal by quercetin of corticotrophin releasing factor induced anxiety-and depression-like effect in mice.

PB Pravinkumar Bhutada, YM Yogita Mundhada… - 2010 - cabidigitallibrary.org
Quercetin is a bioflavonoid reported to produce variety of behavioral effects like anxiolytic,
antidepressant, etc. Recent gathering evidences indicated that quercetin attenuates stress-
induced behavioral and biochemical effects. It also decreases CRF expression in the brain.
As CRF is commonly implicated in the high-anxiety and depression, we hypothesized that
quercetin may involve CRF in its anxiolytic-and antidepressant-like effects. To support such
possibility, we investigated the influence of quercetin on CRF or CRF antagonist …
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