Rheumatoid Arthritis (RA) is an autoimmune disease leading to progressivedestruction and deformity of joint causingdifferent degrees of daily activitieslimitations. Exercise is a key component of nonpharmacological management, helps patients to maintain mobility and function. The current studyaimed to evaluate the change of rheumatoid arthritis patients' perception toward exercise and physical activity level. A quasi-experimental research design was used. the sample consists of 100 rheumatoid arthritis patientsalong 6 months. Two tools were used for data collection; patient health relevant information sheet, it includes two main parts (1) Patient s' demographic data, and medical history.(2) Interview based questionnaire (to assess patients' knowledge about RA) and the arthritis impact measurement scales (aims2-sf). There were a statistically significant higher knowledge score in follow up test (after 2-months)(87%±9.1%) compared to posttest (after 1-month)(79.7%±10.9%) and pre-test results (20.1%±20.9%) compared to control group. There wasstatistically significant improvement in physical functioning, affect, social interaction, role, and symptoms in study group compared to control group as score was not statistically significantly different at pretest (1.000) but highly statistically significantly different in posttest (after one months)(< 0.0005) and follow-up (after two months)(< 0.0005). The perception of the study group about exercise and physical activity improved significantly after health educational instruction implementation compared to the control. provide rheumatoid arthritis patients adequate knowledge and skills about exercise and physical activity to change their perception.