Role of the PI3K/AKT (mTOR and GSK3β) signalling pathway and photobiomodulation in diabetic wound healing
SW Jere, NN Houreld, H Abrahamse - Cytokine & Growth Factor Reviews, 2019 - Elsevier
Activated phosphatidylinositol 3 kinase/Protein kinase B (PI3K/AKT) signalling with
increased or reduced mTOR and GSK3β activity influences the wound repair process.
Diabetic wounds, usually ulcerated, are characterised by reduced growth factors and
cellular performance. The occurrence of diabetic ulcers is linked to peripheral arterial
disease, neuropathy, and wound contamination. Lasers or light emitting diodes (LEDs)
provide photon energy with therapeutic benefits (Photobiomodulation-PBM), and has been …
increased or reduced mTOR and GSK3β activity influences the wound repair process.
Diabetic wounds, usually ulcerated, are characterised by reduced growth factors and
cellular performance. The occurrence of diabetic ulcers is linked to peripheral arterial
disease, neuropathy, and wound contamination. Lasers or light emitting diodes (LEDs)
provide photon energy with therapeutic benefits (Photobiomodulation-PBM), and has been …
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