… of STAT3, and highlight recent discoveries, with a specific focus on STAT3 function in the
immune … Our goal is to spur investigation on mechanisms by which aberrant STAT3 function …

… of the immune system are not well understood. Here we show that Stat3 signaling plays a …
Targeted disruption of Stat3 signaling in APCs resulted in priming of antigen-specific CD4 + …

… STAT1-driven anti-tumour immune responses and STAT3-mediated immune modulatory …
immune responses. Therefore, STAT3 has emerged as a crucial target for cancer therapy and …

… A classic example of this dichotomy is the case of IL-6 and IL-10; both are potent STAT3 …
in the duration and or intensity of STAT3 signaling underlie the disparity, but this may not be …

… that Stat3 signaling restrains natural tumor immune surveillance and that inhibiting
hematopoietic Stat3 in tumor-bearing hosts elicits multicomponent therapeutic antitumor immunity. …

… tumor-interacting immune cells has been … of Stat3 in tumor immune evasion and suppression.
We will devote much of this review on recent findings that suggest the involvement of Stat3 …

… signaling cascades are key regulators of the differentiation and function of cells of the
immune … Modulation of TSC–mTOR signaling on immune cells in immunity and autoimmunity. …

… underlying Stat3-mediated immune suppression may … Stat3 in tumor-induced immune
suppression and discuss different therapeutic approaches involving abrogation of Stat3 signaling …

… Therefore, targeting the STAT3 signaling pathway … of STAT3 signaling pathway in
tumorigenesis and its immune regulation, and highlight the current status for the development of …

… role for STAT3 in cancer … STAT3 signaling and tumor-associated immune suppression.
Here, we summarize recent reports related to the negative effect of STAT3 on cancer immunity …