Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric …
WY Liu, J Jin, Y Tang, N Li, Y Tang, J Wang… - Journal of Geriatric …, 2021 - Elsevier
Background and purpose Comprehensive geriatric assessment (CGA) is a diagnostic
method to assess the physical and mental health status of older patients. The purpose of this
study was to assess the safety and efficacy of preoperative concurrent chemoradiotherapy
(preCRT) for intermediate or locally advanced rectal cancer in older people who were
classified as “fit” by CGA. The interim analysis focusing on safety was reported here as the
first part of this trial. Methods and materials This is a single arm, multicenter, phase II trial …
method to assess the physical and mental health status of older patients. The purpose of this
study was to assess the safety and efficacy of preoperative concurrent chemoradiotherapy
(preCRT) for intermediate or locally advanced rectal cancer in older people who were
classified as “fit” by CGA. The interim analysis focusing on safety was reported here as the
first part of this trial. Methods and materials This is a single arm, multicenter, phase II trial …
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