Scalable robotic biofabrication of tissue spheroids
AN Mehesz, J Brown, Z Hajdu, W Beaver… - …, 2011 - iopscience.iop.org
Abstract Development of methods for scalable biofabrication of uniformly sized tissue
spheroids is essential for tissue spheroid-based bioprinting of large size tissue and organ
constructs. The most recent scalable technique for tissue spheroid fabrication employs a
micromolded recessed template prepared in a non-adhesive hydrogel, wherein the cells
loaded into the template self-assemble into tissue spheroids due to gravitational force. In this
study, we present an improved version of this technique. A new mold was designed to …
spheroids is essential for tissue spheroid-based bioprinting of large size tissue and organ
constructs. The most recent scalable technique for tissue spheroid fabrication employs a
micromolded recessed template prepared in a non-adhesive hydrogel, wherein the cells
loaded into the template self-assemble into tissue spheroids due to gravitational force. In this
study, we present an improved version of this technique. A new mold was designed to …
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