[PDF][PDF] Sequence variation in eNOS (Glu298Asp) gene and its impact on coronary artery disease: North Indian Study

R Tripathi, V Arya, PK Singh, S Agarwal - Ann Biol Res, 2010 - academia.edu
Endothelium-derived nitric oxide (NO) synthesized from L-arginine by endothelial nitric
oxide synthase (eNOS) encoded by the NOS3 gene. Polymerase chain reaction restriction
fragment length polymorphism (PCR-RFLP) analysis of NOS3 identifies G to T substitution at
984 position of exon 7 which changes Glu to Asp amino acid at codon 298. We have done
casecontrol association study to investigate the relationship between Glu298Asp variant and
coronary artery disease (CAD) of North Indian origin. The study consists of 199 unrelated …

Sequence variation in eNOS (Glu298Asp) gene and its impact on coronary artery disease: North Indian Study.

RT Rajneesh Tripathi, VA Vandana Arya, PK Singh… - 2010 - cabidigitallibrary.org
Endothelium-derived nitric oxide (NO) synthesized from L-arginine by endothelial nitric
oxide synthase (eNOS) encoded by the NOS3 gene. Polymerase chain reaction restriction
fragment length polymorphism (PCR-RFLP) analysis of NOS3 identifies G to T substitution at
984 position of exon 7 which changes Glu to Asp amino acid at codon 298. We have done
case-control association study to investigate the relationship between Glu298Asp variant
and coronary artery disease (CAD) of North Indian origin. The study consists of 199 …
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