Serum creatinine and alkaline phosphatase levels are associated with severe chronic periodontitis

AL Caúla, R Lira‐Junior, EMB Tinoco… - Journal of periodontal …, 2015 - Wiley Online Library
AL Caúla, R Lira‐Junior, EMB Tinoco, RG Fischer
Journal of periodontal research, 2015Wiley Online Library
Background and objective Periodontitis may alter systemic homeostasis and influence
creatinine and alkaline phosphatase levels. Therefore, the aim of this study was to evaluate
the relationship between severe chronic periodontitis and serum creatinine and alkaline
phosphatase levels. Material and Methods One hundred patients were evaluated, 66 with
severe chronic periodontitis (test group) and 34 periodontally healthy controls (control
group). Medical, demographic and periodontal parameters were registered. Blood sample …
Background and objective
Periodontitis may alter systemic homeostasis and influence creatinine and alkaline phosphatase levels. Therefore, the aim of this study was to evaluate the relationship between severe chronic periodontitis and serum creatinine and alkaline phosphatase levels.
Material and Methods
One hundred patients were evaluated, 66 with severe chronic periodontitis (test group) and 34 periodontally healthy controls (control group). Medical, demographic and periodontal parameters were registered. Blood sample was collected after an overnight fast and serum creatinine and alkaline phosphatase levels were determined.
Results
There were significant differences between test and control groups in ethnicity, gender and educational level (p < 0.05). Patients with periodontitis showed a lower mean creatinine level (p < 0.05) and higher mean alkaline phosphatase level (p < 0.001) than the control group. There were significant correlations between periodontal parameters and serum creatinine and alkaline phosphatase levels.
Conclusion
Severe chronic periodontitis was associated to lower creatinine and higher alkaline phosphatase levels.
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