Signal enhancement of glutamine and glutathione by single-step spectral editing
L An, MF Araneta, M Victorino, J Shen - Journal of Magnetic Resonance, 2020 - Elsevier
A single-step spectral editing approach using an always-on editing pulse was proposed to
enhance the signals of strongly coupled spins. Specifically, a single-step spectral editing
sequence with an always-on editing pulse applied at 2.12 ppm was used to enhance
glutamine (Gln) and glutathione (GSH) signals at TE= 56 ms on a 7 T scanner. Density
matrix simulations demonstrated that the current method (TE= 56 ms) led to large signal
enhancement of at least 61% for Gln and 51% for GSH compared to a previous single-step …
enhance the signals of strongly coupled spins. Specifically, a single-step spectral editing
sequence with an always-on editing pulse applied at 2.12 ppm was used to enhance
glutamine (Gln) and glutathione (GSH) signals at TE= 56 ms on a 7 T scanner. Density
matrix simulations demonstrated that the current method (TE= 56 ms) led to large signal
enhancement of at least 61% for Gln and 51% for GSH compared to a previous single-step …
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