1 天前 - … these two pathways and their effects on immune signaling. … into additional targeted
therapies for melanoma patients. … target genes that regulate multiple signaling pathways. To …

4 天前 - … , the PI3K/AKT signalling pathway has been proven vital in … Citation2 BRAF-targeted
therapy has been applied in the … PI3K/AKT signalling pathway through the hyperactivation …

4 天前 - … and GSEA to compare biological signaling pathways between high and low CD24
… that melanoma patients with high CD24 expression were less responsive to PD-1 therapy. …

5 天前 - … of skin cancer, the main one is the dysregulation in the Hedgehog signaling pathway
… of BCC; targeted therapy, that has increased the percentage of cure rate of the disease. …

5 天前 - … signal-regulated kinase (MEK) signaling pathways [4,5]. Although the emergence
of immune and targeted therapies … life expectancy of patients with melanoma, some patients …

7 天前 - … leading to constitutive MEK and ERK signaling. In spite of initial … melanoma treatment.
Recently it was shown that the p53 pathway contributes to acquired resistance to targeted …

7 天前 - … (DDR)/actomyosin signaling pathway. In silico analysis further … of melanoma cells
to targeted therapy (22,35,41). We first assessed the contribution of USP9X in melanoma cell …

8 天前 - … Therefore, in a melanoma mouse model, MYH9 may act as a potential tumor …
and targeted therapy by regulating the MAPK, PI3K/Akt, and Wnt/β-catenin signaling pathways. …

8 天前 - … cells, followed by examination of the PI3K signaling pathway and Gli1/Gli3 expression
… speci c target therapies. In order to increase the metastatic capacity, melanoma cells …

8 天前 - … signaling pathways. In order to determine the transcriptomic signature dependent
on the resistance to BRAFi targeted therapy and associated with p53 pathway… BRAFi therapy. …