您是不是要找: Signaling via the NF κB system

Signaling via the NFκB system

S Mitchell, J Vargas, A Hoffmann - … Reviews: Systems Biology …, 2016 - Wiley Online Library
… Computation 2014, 2:131), in this review we aim to summarize the current understanding of
the NFκB signaling system itself, the molecular mechanisms, and systems properties that are …

[HTML][HTML] Signaling via NF-κB in the nervous system

B Kaltschmidt, D Widera, C Kaltschmidt - Biochimica et Biophysica Acta …, 2005 - Elsevier
NF-κB in the nervous system. This article contains a listing of NF-κB activators and inhibitors
in the nervous system… Synaptic NF-κB activated by glutamate and Ca 2+ will be presented in …

NFκB signaling

E O'Dea, A Hoffmann - … Reviews: Systems Biology and Medicine, 2009 - Wiley Online Library
… Such signals therefore liberate NF-κB from the canonical and … The p50 and p52 proteins
are produced via proteolytic … , dimerization via the RHD by p100 or p105 with other NF-κB

Signaling to NF-κB

MS Hayden, S Ghosh - Genes & development, 2004 - genesdev.cshlp.org
… The biological system in which NF-κB plays the most important … NF-κB. However, there is
significant variability in fundamental aspects of these pathways, for example, TNFα signaling via

NF-κB signaling pathways: role in nervous system physiology and pathology

S Mincheva-Tasheva, RM Soler - The Neuroscientist, 2013 - journals.sagepub.com
system development and pathology. The effects caused by NF-κB activity in the nervous
system … Genes regulated by NF-κB dimers are mainly responsible for these functions, and the …

Transcriptional regulation via the NF-κB signaling module

A Hoffmann, G Natoli, G Ghosh - Oncogene, 2006 - nature.com
… that determine NF-κB dimer formation and the signal-processing characteristics of the
signaling module. We identify NF-κB–κB site interaction specificities and dynamic control of …

NF-κB, IκB, and IKK: integral components of immune system signaling

MC Mulero, T Huxford, G Ghosh - Structural immunology, 2019 - Springer
… Contrary to IKK1/α and IKK2/β, NEMO/IKKγ lacks kinase catalytic activity and instead serves
an essential accessory role in activation of NF-κB via the canonical signaling pathway. The …

A single NFκB system for both canonical and non-canonical signaling

VFS Shih, R Tsui, A Caldwell, A Hoffmann - Cell research, 2011 - nature.com
… hand, inhibits signaling upstream of IKK via its … the NFκB signaling system that accounts for
the intricate molecular mechanisms pertaining to both canonical and non-canonical signaling

Diversity and regulation in the NF-κB system

C Wietek, LAJ O'Neill - Trends in biochemical sciences, 2007 - cell.com
… We propose that this promiscuity might help explain the many of roles of NF-κB in specialized
… target sequence will all define the composition and activity of multimeric NF-κB complexes. …

The NF-κB/IκB signaling system: a molecular target in breast cancer therapy

JT Wu, JG Kral - Journal of Surgical Research, 2005 - Elsevier
… High concentrations of leptin also promote an aggressive breast cancer phenotype via NF-κB
activation [91]. Crandall et al. demonstrated that human adipocytes secrete plasminogen …
您是不是要找: Signaling via the NF κB system