过去一年中添加的文章,按日期排序

The Hippo-YAP1/HIF-1α pathway mediates arsenic-induced renal fibrosis

W Di, Y Li, L Zhang, Q Zhou, Z Fu, S Xi - Environmental Research, 2024 - Elsevier
15 天前 - … YAP1 is involved in arsenic-induced renal fibrosis through activation of HIF-1α (A) …
YAP1: Yes-associated protein 1; HIF-1α: hypoxia inducible factor 1α; PAI-1: plasminogen …

Jian-Pi-Yi-Shen Formula Ameliorates Renal Fibrosis-Induced Anemia in Rats with Chronic Kidney Disease

H Huang, S Huang, C Li, C Zhang, R Wang… - Available at SSRN … - papers.ssrn.com
29 天前 - signaling pathways. Our 50 findings highlight that JPYS is a favorable therapeutic
strategy for renal fibrosis… HIF-PHI Hypoxia inducible factorprolyl hydroxylase inhibitor ANOVA …

Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice

Y Shi, D Wang, Y Li, G Li, M Liu, Z Zhou, M Wu, S Song… - 2024 - researchsquare.com
41 天前 - … In addition, MitoSOX Red staining revealed hypoxiainduced mitochondrial ROS …
-STING signalling pathway, and promoted in ammatory responses which contributed to the …

The SP1/SIRT1/ACLY signaling axis mediates fatty acid oxidation in renal ischemia–reperfusion-induced renal fibrosis

H Wu, L Wang, P Kang, X Zhou, W Li, Z Xia - International …, 2024 - Elsevier
70 天前 - … adeno-associated virus that overexpresses SIRT1 was injected into mice to explore
the function of SIRT1 in renal fibrosis induced by renal IRI. In vitro, hypoxia/reoxygenation (H…

… heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway

R Xu, Y Bi, X He, Y Zhang, X Zhao - Journal of Ethnopharmacology, 2024 - Elsevier
77 天前 - … p38MAPK signaling pathway is involved in cardiac remodeling, myocardial fibrosis,
… Chen's team investigated that the p38MAPK/NF-κB signaling pathway is also involved in …

[HTML][HTML] Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Sini decoction (四逆汤) against renal fibrosis

W Yan, D Fanying, LIU Shiqi… - Journal of Traditional …, 2024 - ncbi.nlm.nih.gov
91 天前 - … of synaptic transmission (glutamatergic), KEGG analysis of the network
pharmacology predicts that the signaling pathways involved in alleviating Rf may be the TGF-β …

[HTML][HTML] High-Dose Fenofibrate Stimulates Multiple Cellular Stress Pathways in the Kidney of Old Rats

A Wrońska, J Kieżun, Z Kmieć - International Journal of Molecular …, 2024 - mdpi.com
106 天前 - … that FF may mitigate renal fibrosis in hypertensive rats [8], … under transcriptional
control of Hypoxia Inducible Factor 1 (HIF-… signaling pathways plays a role in some settings [54]. …

[HTML][HTML] Integrative analysis of chromatin accessibility and transcriptome landscapes in the induction of peritoneal fibrosis by high glucose

Q Song, P Wang, H Wang, M Pan, X Li, Z Yao… - Journal of Translational …, 2024 - Springer
106 天前 - … -induced pathological fibrotic changes in HPMCs. This analysis identified hub
genes, signaling pathways, and key transcription factors involved in peritoneal fibrosis and …

[HTML][HTML] … Acute to Chronic: Unraveling the Pathophysiological Mechanisms of the Progression from Acute Kidney Injury to Acute Kidney Disease to Chronic Kidney …

TH Yeh, KC Tu, HY Wang, JY Chen - International Journal of Molecular …, 2024 - mdpi.com
140 天前 - kidney fibrosis and loss of renal function [16]. There are severe molecules involved
in the complicated process of renal fibrosis… /SMAD, and Hippo signaling pathways (Figure 1). …

[HTML][HTML] Kidney Fibrosis and Oxidative Stress: From Molecular Pathways to New Pharmacological Opportunities

F Patera, L Gatticchi, B Cellini, D Chiasserini… - Biomolecules, 2024 - mdpi.com
149 天前 - … However, several studies have shown that fibrosis can be … three pathways that link
oxidative stress and kidney fibrosis, … signaling pathway, and (iii) the hypoxia-inducible factor (…