The objective of the current analysis is to study the influence of MHD on flow of an ethylene glycol-based nanofluid containing copper nanoparticles through a exponential stretching sheet. Several parameters including Dufour, thermal radiation, Magnetohydrodynamic (MHD), and Eckart number, were investigated for their impacts on fluid flow, heat and mass transfer profiles, and thermal convective boundary conditions, while Navier velocity slip was also considered. The basic PDEs are transformed into nondimensional ODEs using appropriate transformations and numerically characterized by bvp4c. The graphs examine the influence of relevant parameters on heat and mass transfer profiles. The velocity profile decrease with slip effect. As the Biot number increased, the thermal layer became thicker. The Nusselt number are the decline functions of magnetic field, Eckert number and Brownian diffusion but the local Sherwood number enhanced with these parameters. The Nusselt number intensifies with radiation parameter Rd, slip parameter λ and Biot numberBi. The temperature and concentration profiles rises with increase in Nt.