Sodium acetate and androgen receptor blockade improve gestational androgen excess-induced deteriorated glucose homeostasis and antioxidant defenses in rats …

TO Usman, ED Areola, OO Badmus, IK Kim… - The Journal of …, 2018 - Elsevier
Nutritional challenges and androgen excess have been implicated in the development of
gestational diabetes and poor fetal outcome, but the mechanisms are not well delineated.
The effects of short chain fatty acid (SCFA) on glucose dysmetabolism and poor fetal
outcome induced by gestational androgen excess is also not known. We tested the
hypothesis that blockade of androgen receptor (AR) and suppression of late gestational
androgen excess prevents glucose dysmetabolism and poor fetal outcome through …

A4073 Sodium acetate and androgen receptor blockade improve gestational androgen excess-induced deteriorated glucose homeostasis and antioxidant defenses in …

E Areola, O Badmus, U Taofeek… - Journal of Hypertension, 2018 - journals.lww.com
Objectives: Nutritional challenges and androgen excess have been implicated in the
development of gestational diabetes and poor fetal outcome, but the mechanisms are not
well delineated. The effects of short chain fatty acid (SCFA) on glucose dysmetabolism and
poor fetal outcome induced by gestational androgen excess is also not known. We tested
the hypothesis that blockade of androgen receptor (AR) and suppression of late gestational
androgen excess prevents glucose dysmetabolism and poor fetal outcome through …
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