… of alternative possible mechanisms of fragmentation for molecular crystals. In fact, very early
work … We suggest that there are four classes of possible mechanisms for sonofragmentation: …

… sonofragmentation, we examine here fundamental experiments on the fragmentation of organic
molecular crystals … of slurries of brittle molecular and ionic crystals leads to rapid fracture …

… Sonication of molecular crystals causes sonofragmentation by means of direct interactions
between particles and shockwaves. Suslick et al. explored the sonication of an aspirin slurry …

… The impact of sonofragmentation on molecular crystals will also be discussed. … to the
sonofragmentation of molecular crystals. We anticipate the impact of sonofragmentation on crystal …

… molecular solids.8 To understand the breakage of brittle materials, we isolated each of these
possible contributions to the sonofragmentation of ionic crystals … detail for molecular crystals,…

… crystals or other foreign materials. We will review the potential mechanisms for the breakage
of molecular crystals … of acetylsalicylic acid (aspirin) crystals as a model API. Surprisingly, …

… The sonofragmentation of ionic and molecular crystals is discussed … molecular crystals,
crystal breakage occurred not by interparticle collision but by direct interactions between crystals …

… nucleation by disaggregation or sonofragmentation of existing crystals. In addition, for … rate
of molecular crystals, which have different physical properties compared to metallic crystals (…

… High-intensity ultrasound is also employed in the preparation of molecular crystals, although
the field remains in its infancy. The effects of high-intensity ultrasound on the preparation of …

… interactions are the main source of particle breakage for molecular crystals. (5) Low ultrasonic
frequencies will … Consequently, the degree of sonofragmentation will be low as well. …