Spectrophotometric determination of some catecholamine drugs using metaperiodate
ME El-Kommos, FA Mohamed… - Journal of the Association …, 1990 - academic.oup.com
ME El-Kommos, FA Mohamed, AS Khedr
Journal of the Association of Official Analytical Chemists, 1990•academic.oup.comA rapid spectrophotometric procedure for the determination of Isoprenaline salts, levodopa,
dopamine hydrochloride, and dobutamine hydrochloride, either In the drug substances or In
pharmaceutical formulations, Is described. The method is based on the development of
orange, red, or violet products with sodium metaperiodate in an aqueous alcoholic medium.
The reaction is suggested to proceed via oxidative cyclizatlon of the catecholamine to form
an amlnochrome. The wavelengths of maximum absorption range from 465 to 520 nm. The …
dopamine hydrochloride, and dobutamine hydrochloride, either In the drug substances or In
pharmaceutical formulations, Is described. The method is based on the development of
orange, red, or violet products with sodium metaperiodate in an aqueous alcoholic medium.
The reaction is suggested to proceed via oxidative cyclizatlon of the catecholamine to form
an amlnochrome. The wavelengths of maximum absorption range from 465 to 520 nm. The …
Abstract
A rapid spectrophotometric procedure for the determination of Isoprenaline salts, levodopa, dopamine hydrochloride, and dobutamine hydrochloride, either In the drug substances or In pharmaceutical formulations, Is described. The method is based on the development of orange, red, or violet products with sodium metaperiodate in an aqueous alcoholic medium. The reaction is suggested to proceed via oxidative cyclizatlon of the catecholamine to form an amlnochrome. The wavelengths of maximum absorption range from 465 to 520 nm. The structure of the cyclization product was confirmed by ultraviolet, infrared, and nuclear magnetic resonance spectroscopy and microanalysis data.
Oxford University Press以上显示的是最相近的搜索结果。 查看全部搜索结果