Statins with potential to control periodontitis: From biological mechanisms to clinical studies
RDP de Carvalho, RCV Casarin, PO de Lima… - Journal of Oral …, 2021 - Elsevier
Background Statins are widely used for the treatment of hyperlipidemia. However, these
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral
diseases, such as periodontitis. Highlight This review aimed to identify preclinical,
observational, and clinical studies that evaluate the effects and biological mechanisms of
statins on oral cells and tissues and those using these drugs to treat periodontitis. A
literature survey has been conducted in PubMed using combinations of the …
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral
diseases, such as periodontitis. Highlight This review aimed to identify preclinical,
observational, and clinical studies that evaluate the effects and biological mechanisms of
statins on oral cells and tissues and those using these drugs to treat periodontitis. A
literature survey has been conducted in PubMed using combinations of the …
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