Stimulus dependent properties of mammalian cochlear hair cell mechanoelectrical transduction

AL Scharr, A Ricci - AIP Conference Proceedings, 2018 - pubs.aip.org
Cochlear hair cell stereocilia move semi-independently, shaping the force transfer to
mechanoelectrical transduction (MET) channels, as indicated by the MET current response.
Semi-independent movement of stereocilia was evoked by stimulating inner hair cell (IHC)
bundles from acutely dissected rat cochlea with stiff probes ranging in size from 1 to 10 μm.
MET current responses were recorded using whole-cell patch-clamp electrophysiology.
Small probes directly displaced stereocilia they contacted, and recruited adjacent stereocilia …
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