过去一年中添加的文章，按日期排序
Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency
R Tesla, C Guhl, GC Werthmann, D Dixon… - Nature …, 2024 - nature.com
38 天前 - … boost progranulin levels from the remaining functional GRN allele, thus restoring
progranulin … significantly increase progranulin protein levels in human cellular models, correct …
progranulin … significantly increase progranulin protein levels in human cellular models, correct …
IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis
L Liang, F Zhang, N Feng, B Kuang, M Fan… - … & Molecular Medicine, 2023 - nature.com
301 天前 - … revealed the mechanism by which ERN1 deficiency leads to the structural abnormality
… and proposed a possible functional compensatory mechanism in the absence of ERN1. …
… and proposed a possible functional compensatory mechanism in the absence of ERN1. …