… Only a few type-II endonucleases other than EccRI and EcoRV have been studied in any …
(for recent reviews, see [5,6]). In studying the structure and function of these particular enzymes, …

… It is clear that more non-specific structures are needed to complement their specific … features
of restriction endonucleases will be compared. The emphasis will be on recent structural …

… in our understanding of the structure and function of restriction endonucleases. The …
endonuclease from Escherichia co//, structures soon to be reported for E. coil EcoRV endonuclease …

… features subtypes are classified. All structures of restriction enzymes show a common structural
… Furthermore, two families of enzymes can be distinguished which are structurally very …

… Biology would look like today had Type II restriction enzymes … viral infections, these enzymes
allow unmanageable tangles … developed without Type II restriction enzymes, and certainly …

… -substrate complexes and, even more importantly, of the enzyme-transition state complexes
… discuss our current knowledge of all categories of nuclease save restriction endonucleases, …

… structure–function relationships in those families, and are the centerpiece of this review. Finally,
homing endonucleases … (14 bp) compared to restriction endonucleases, but shorter than …

… restriction endonucleases, we need the structures of the apoenzymes as well as enzyme-…
eukaryotic regulatory proteins share structural motifs with restriction endonucleases whose …

… that has transformed molecular biology and medicine. This review traces the discovery of
restriction enzymes and their continuing impact on molecular biology and medicine. …

… The three-dimensional structures of the type II restriction endonucleases can be roughly
divided into two subfamilies according to the pattern of the DNA ends after cleavage. BamHI [4], …