StuA-Regulated Processes in the Dermatophyte Trichophyton rubrum: Transcription Profile, Cell-Cell Adhesion, and Immunomodulation
TA Bitencourt, J Neves-da-Rocha… - Frontiers in Cellular …, 2021 - frontiersin.org
Fungal infections represent a significant concern worldwide, contributing to human morbidity
and mortality. Dermatophyte infections are among the most significant mycoses, and
Trichophyton rubrum appears to be the principal causative agent. Thus, an understanding of
its pathophysiology is urgently required. Several lines of evidence have demonstrated that
the APSES family of transcription factors (Asm1p, Phd1p, Sok2p, Efg1p, and StuA) is an
important point of vulnerability in fungal pathogens and a potential therapeutic target. These …
and mortality. Dermatophyte infections are among the most significant mycoses, and
Trichophyton rubrum appears to be the principal causative agent. Thus, an understanding of
its pathophysiology is urgently required. Several lines of evidence have demonstrated that
the APSES family of transcription factors (Asm1p, Phd1p, Sok2p, Efg1p, and StuA) is an
important point of vulnerability in fungal pathogens and a potential therapeutic target. These …
[引用][C] StuA-regulated processes in the dermatophyte Trichophyton rubrum: transcription profile, cell-cell adhesion, and immunomodulation
JNR Fonseca, TA Bitencourt, MP Martins, PR Sanches… - Resumos, 2021 - repositorio.usp.br
ReP USP - Detalhe do registro: StuA-regulated processes in the dermatophyte
Trichophyton rubrum: transcription profile, cell-cell adhesion, and immunomodulation …
Trichophyton rubrum: transcription profile, cell-cell adhesion, and immunomodulation …
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