Synthesis, antifungal activity and QSAR of some novel carboxylic acid amides

S Du, H Lu, D Yang, H Li, X Gu, C Wan, C Jia, M Wang… - Molecules, 2015 - mdpi.com
A series of novel aromatic carboxylic acid amides were synthesized and tested for their
activities against six phytopathogenic fungi by an in vitro mycelia growth inhibition assay.
Most of them displayed moderate to good activity. Among them N-(2-(1 H-indazol-1-yl)
phenyl)-2-(trifluoromethyl) benzamide (3c) exhibited the highest antifungal activity against
Pythium aphanidermatum (EC50= 16.75 µg/mL) and Rhizoctonia solani (EC50= 19.19
µg/mL), compared to the reference compound boscalid with EC50 values of 10.68 and 14.47 …

Synthesis, antifungal activity and QSAR of some novel carboxylic acid amides.

DSJ Du ShiJie, LHZ Lu HuiZhe, YDY Yang DongYan… - 2015 - cabidigitallibrary.org
A series of novel aromatic carboxylic acid amides were synthesized and tested for their
activities against six phytopathogenic fungi by an in vitro mycelia growth inhibition assay.
Most of them displayed moderate to good activity. Among them N-(2-(1 H-indazol-1-yl)
phenyl)-2-(trifluoromethyl) benzamide (3c) exhibited the highest antifungal activity against
Pythium aphanidermatum (EC50= 16.75 µg/mL) and Rhizoctonia solani (EC50= 19.19
µg/mL), compared to the reference compound boscalid with EC50 values of 10.68 and 14.47 …
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