Synthesis, characterization, and antioxidant and anticancer activity of 1, 4-disubstituted 1, 2, 3-triazoles
This manuscript describes the synthesis, characterization, antioxidant and anticancer
activities of the six 1, 2, 3-triazole derivatives (7a, 7b, 8a, 8b, 9a and 9b) containing a 1, 4-
disubstitue. All compounds were characterized by 1 H (13 C) NMR, FTIR spectroscopies and
elemental analysis. The crystal structures of triazole derivatives (7b, 8a, and 9a) were
studied by X-ray diffraction studies. The compounds were screened for their radical
scavenging capabilities and the compounds showed comparable antioxidant activities to …
activities of the six 1, 2, 3-triazole derivatives (7a, 7b, 8a, 8b, 9a and 9b) containing a 1, 4-
disubstitue. All compounds were characterized by 1 H (13 C) NMR, FTIR spectroscopies and
elemental analysis. The crystal structures of triazole derivatives (7b, 8a, and 9a) were
studied by X-ray diffraction studies. The compounds were screened for their radical
scavenging capabilities and the compounds showed comparable antioxidant activities to …
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