Synthesis of azomethines derived from cinnamaldehyde and vanillin: In vitro aetylcholinesterase inhibitory, antioxidant and insilico molecular docking studies

S Chigurupati, M Selvaraj, V Mani… - Medicinal Chemistry …, 2018 - Springer
In the present study, we report the synthesis of azomethines derived from cinnamaldehyde
(C1–C3) and vanillin (V1–V3) using ethanol as a green solvent in the presence of triethyl
amine. The synthesized compounds were characterized and investigated for their free
radical scavenging activity and anti-Alzheimer properties by DPPH and acetylcholinesterase
(AChE) inhibition assays. The anti-Alzheimer properties of the compounds were determined
by molecular docking and ADME predictions. Compounds, C1 and V1 were found to be …

[引用][C] Synthesis of azomethines derived from cinnamaldehyde and vanillin: in vitro aetylcholinesterase inhibitory, antioxidant and in silico molecular docking studies

C Sridevi, M Selvaraj, V Mani, JI Mohammad… - Med. Chem. Res, 2018
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