Systematic assessment of clinical outcomes and toxicities of proton radiotherapy for reirradiation

V Verma, JCM Rwigema, RS Malyapa… - Radiotherapy and …, 2017 - Elsevier
Reirradiation (reRT) for locoregional recurrences poses unique challenges and risks; re-
treatment using proton beam radiotherapy (PBT) could prove advantageous. Assessing
clinical outcomes and toxicity profiles, this systematic review comprehensively evaluated
available evidence regarding PBT reRT. Fourteen original investigations across central
nervous system (CNS)(n= 6), head/neck (H&N)(n= 4), lung (n= 2), and gastrointestinal (n= 2)
malignancies were analyzed. PBT for recurrent uveal melanoma achieved 5-year eye …
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